glutathione reductase peroxidase Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging Glutathione Reductase human

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10.1007/s10534-021-00309-w 76

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Abnormally accumulated -syn can alter the number of the ER-mitochondrial contact sites and alter the transport of Ca 2+ ( in vitro and in vivo ( MicroRNA and Mitochondrial Anomalies in Parkinsons Disease MicroRNAs (miRNAs) are ncRNAs, 1825 bases in length, that serve as regulators that affect stability and translation of mRNA targets by directing RNA-induced silencing complex (RISC) to the 3-UTR, more details see It has been reported that miR-133b is downregulated in the midbrain of PD patients, which indirectly decreases the expression of vesicular monoamine transporter 2 (VMAT2) by downregulating paired-like homeodomain transcription factor 3 (Pitx3) and altering the expression of dopamine transporter (DAT) through the same process that alters VMAT2 expression ( in vitro ( in vitro (Zhou et al., 2019