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This was further supported by correlation between these outcomes and Bu levels following the first dose

The glutathione cycle: glutathione metabolism beyond the glutamyl cycle

Epidemiology and risk factors for rheumatoid arthritis development

Moreover, thioredoxin reductase also contributes as an antioxidant enzyme by reducing hydroperoxides and functioning as a NADPH-dependent dehydroascorbate reductase to recycle vitamin C (25)