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Adrenal dysfunction may be addressed with stress reduction, proper sleep, and the use of nutrients such as vitamin C, vitamins B5, and B6, as well as adaptogenic herbs such as ginseng compounds, licorice root (glycyrrhiza glabra), withania (ashwagandha), and others.44,45 Stressful physiologic conditions such as pregnancy and trauma can induce a hypercortisol condition

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At the same time, selective abrogation of glutamine anabolism in vivo in the CAFs has been shown to inhibit ovarian tumor growth in mice [67] (Fig

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