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At present, there is relatively little information on the incidence of the five common haplotypes in populations other than Caucasians

235 The above evidence demonstrates that the MS, SLE, RA, and SS patients have active EBV lytic replication

However, conditions affecting the gastrointestinal tractincluding pernicious anaemia, Crohn's disease, coeliac disease, or gastric surgerycan significantly impair absorption, necessitating alternative supplementation routes such as intramuscular hydroxocobalamin injections, which deliver B12 directly into the bloodstream

No large-scale phase 3 trials have been completed

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