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I., & Kenley, D

In rare cases, both XR and IR formulations can lead to more severe side effects, including: Cardiovascular issues (e.g., heart attack, stroke) Psychiatric symptoms (e.g., aggression, hallucinations) Allergic reactions (e.g., rash, difficulty breathing) It is crucial to seek immediate medical attention if any severe side effects occur, regardless of the formulation being used

SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor

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However, much of the available evidence originates from laboratory and animal studies rather than controlled human clinical trials