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Description

Pathomechanics of peripheral nerve loading

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The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies

Under neuropathological conditions, impaired activity of peroxisome proliferator-activated receptor (PPAR) can inhibit lactoferrin (Ltf) transcription, leading to increased free iron concentrations and increased lipid peroxidation levels in neurons, thereby exacerbating ferroptosis