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By noticing that the peptide did not show evidence of the ability to become lethal and was not toxic, researchers begin to look for ways that it could have a healing effect on rodent test subjects that had ileoileal anastomosis

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Transected rat Achilles tendons treated with the peptide showed not only faster healing but qualitatively better tissue organization

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Key Research Points at a Glance A 15-amino-acid fragment of a gastric-juice-derived protective protein, first characterised in the early 1990s Primary research mechanisms: angiogenesis (VEGF pathway) and gastric/gut-lining signalling Secondary mechanisms under study: growth factor modulation (EGF, FGF) and nitric oxide system interaction Frequently co-researched with TB-500 despite acting through an unrelated mechanism The large majority of published research is pre-clinical (in-vitro and animal-model), not human clinical data Notably stable across a wider pH/temperature range than many comparable research peptides What Is BPC-157