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Since DFO was first discovered to have an inhibitory effect on ferroptosis caused by erastin and RSL3, DFO is the drug most widely used to inhibit lipid peroxidation-mediated ferroptosis under various conditions ( in vivo and in vitro ( Deferasirox Deferasirox is a membrane-permeable iron chelator and the first oral medication approved by the Food and Drug Administration (FDA) for chronic iron overload in the body caused by multiple blood transfusions

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Theodoridis X, Grammatikopoulou MG, Stamouli EM, et al