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Clinical Significance: Acyl Carnitine Translocase Deficiency Mutations in the SLC25A20 gene , which encodes Acyl Carnitine Translocase , lead to Carnitine-Acylcarnitine Translocase Deficiency (CACT Deficiency)

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Neuronal mitochondrial dysfunction resulting in nitro-oxidative stress [42] is regarded as one of the most important contributors to CIPN development [23, 29, 43]

The most distressing aspects of PCOS are inability to ovulate and become pregnant, weight gain, hair loss, unwanted facial and body hair growth, and acne