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Advanced experimental systems, such as ovarian organoids, may further improve mechanistic studies

Considering that oxidative stress plays a crucial role in the pathogenesis of SSc, GGT may be a marker associated with the development of SSc. To examine the link between gamma-glutamyl transferase levels and the risk for SSc, Kwon and colleagues conducted a nationwide, retrospective cohort study of more than 6 million adults without SSc from the Korean National Health Insurance Service database

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Nowadays, this is the unique condition of IGF-I deficiency where rhIGF-I is approved (as will be stated in Current therapeutic options section)

Ferroptosis inhibition in long-lived plasma cells might provide a strategy to prolong antibody responses in vaccination or autoimmune diseases where excessive autoantibody production is a concern (7478)