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Mitochondrial functions and homeostasis maintenance Mitochondrial functions Mitochondria are energy-producing cellular organelles that generate energy in the form of ATP via oxidative phosphorylation (OXPHOS) performed by the electron transport chain (ETC) complexes

3.1.2 In vivo animal studies It is known that stress negatively influences the homeostasis of the circadian rhythm, which results in disturbance of the hypothalamic-pituitary-gonadal axis

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Mice were euthanized at humane endpoints (i.e., when the tumor size exceeded a total of 20 mm in length, when ulceration occurred, or when weight loss exceeded 20%)