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Description

Bru-seq-based transcription profiling unravelled novel roles for GSTO1 in cholesterol metabolism, oxidative and endoplasmic stress responses, cytoskeleton and cell migration

The only human trial ever registered (NCT02637284) was cancelled in 2016 without publishing results

Other PTMs, such as methylation, are more context dependent, with the resultant chromatin state being determined by the specific amino acids in the histones that are modified, and the combination of PTMs on neighboring histones

Yes, it supports liver detoxification and regeneration, aiding in the management of fatty liver

The administration into the blood of Hu5F9-G4 revealed that it can pass through the blood-brain endothelial barrier (BBB) apparently even when the tumor was not present