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Description

EMT increases reliance on mitochondrial isocitrate dehydrogenase 2 (IDH2)-mediated reductive carboxylation of glutamine for fatty acid synthesis, reducing glycolytic flux and glutathione production

This Research Topic is part of a series with: The changing faces of glutathione, a cellular protagonist., Volume II Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases

HIV-1 myristoylated Nef treatment of murine microglial cells activates inducible nitric oxide synthase, NO 2 production and neurotoxic activity

We adjust buffer systems and enrichment conditions based on matrix type to optimize recovery and specificity

Skin Aging Of all the organs, the skin is the most conspicuous to display signs of aging or dermal changes, which are due to chronological (intrinsic) and photoaging (extrinsic) mechanisms [2, 10, 14]