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The diverse forms of regulated necrosis may be interrelated, share molecular pathways and cell defence mechanisms and coexist in the same kidney disease, affecting different cell types or the same cell type synchronously or sequentially

3.1.2 Adverse effects of using thiazolidinediones One of the main adverse effects associated with PPAR receptor activation is the enhanced proliferation of peripheral adipocytes, which leads to increased uptake of free fatty acids

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L-C19 chemosensory disfunction significantly reduces quality of life, with negative implications in mental health: anxiety, depression, loss of appetite, weight changes, even work and study difficulties or social and interpersonal limitations (80)