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Almost every discussion of GHK-Cu for skin quietly assumes that the copper peptide works the same way no matter how it enters the body but the central research question of this article is far narrower and far more honest: does the published human evidence for smoother, firmer, better-remodeled skin come from a cream or from a needle

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First, the lower dose outperformed the higher dose, suggesting that copper peptide concentration is not a "more is better" situation