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Proc Natl Acad Sci USA 97:1438214387 Philip P, Sagaspe P, Taillard J et al (2019) Acute intake of a grape and blueberry polyphenol-rich extract ameliorates cognitive performance in healthy young adults during a sustained cognitive effort

The former mechanism is preferred because RS scavengers can be consumed during the reaction and may generate toxic radicals derived from the chelators (Halliwell and Gutteridge, 2015)