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Different peptides can interact, aggregate, or inactivate each other when combined in solution

Michot JM, Annereau M, Danu A, Legoupil C, Bertin L, Chahine C, Achab N, Antosikova A, Cerutti A, Rossignol J, Ghez D, Willekens C, Dartigues P, Lazarovici J, Lemare F, Ribrag V (2020) High-dose cyclophosphamide for hard-to-treat patients with relapsed or refractory B-cell non-Hodgkins lymphoma, a phase II result

S.MontellierE.et al (2011)

During liver failure, reduced usage of ammonia as a substrate in the ammonia detoxification pathway (urea cycle) and portosystemic shunting increases ammonia accumulation in the systemic circulation (83)