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Potential of ferroptosis and ferritinophagy in migraine pathogenesis

Washington, WA: National Academies Press, 10.2307/1525495 Guide for the Care and Use of Laboratory Animals

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Mechanistic studies reveal that lipoic acid can inhibit ferroptosis by downregulating transferrin receptor expression and upregulating GPX4, thereby protecting neurons involved in learning and memory and improving cognitive function ( Figure 4 ) (190)