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Peptides that elevate IGF-1, including CJC-1295, Ipamorelin, and Tesamorelin, raise a legitimate question about hormone-sensitive and growth-sensitive cancer risk that women in their 50s should hear honestly before starting

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The FDA's concerns about immunogenicity at certain injection routes and inconsistent pharmaceutical-grade characterization across suppliers are legitimate issues not invented ones

(1992) published foundational work in the Journal of Molecular Endocrinology characterizing Long R3 IGF-1's enhanced potency in cell proliferation assays compared to native IGF-1

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