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For example, research into the role of matrix metalloproteinases (MMPs), enzymes that degrade extracellular matrix components, provides insights into how excessive MMP activity might contribute to ligament degradation and injury risk

Cancer Dis-cov 2016;6(6): 66479

A hallmark of cancer metabolism

However, no metabolomic studies have compared the multiple stages of MA exposure corresponding to drug reward, extinction, and reinstatement, which characterize the development of drug dependence