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Carrier-frequency data for MT-RNR1 variants are best characterized in European cohorts, with fewer population-level estimates elsewhere

Lowrey, P.L., Takahashi, J.S., Genetics of the mammalian circadian system: Photic Entrainment, Circadian Pacemaker Mechanisms, and Posttranslational Regulation

however, large-scale trials are needed, and identifying the minimum effective dose range for L-citrulline is necessary , considering a potential effect of high doses on nitrogen balance

The authors concluded that ARA supplementation did not support a mechanistic link between ARA supplementation and short-term anabolism, but may increase translation capacity

"This is how regulation works recognising that there is activity that is not in keeping with the safety of the community and taking action to address it." The TGA says its investigations are ongoing