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doi: 10.3389/fmed.2025.1569732 Received 01 February 2025 Accepted 21 April 2025 Published 08 May 2025 Volume 12 - 2025 Edited by Divya Bhatia, NewYork-Presbyterian, United States Reviewed by Muhammad Imran Khan, Chonnam National University, Republic of Korea Edwin Patino, NewYork-Presbyterian, United States Updates Copyright 2025 Fu, Chen, Li and Peng

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Consistent with other reports regarding C-terminal truncations of its ortholog HNF4 61 , truncating the ligand-binding domain of NHR-49 altered its nucleocytoplasmic distribution, favoring a more pronounced nuclear localization under ad libitum feed conditions when compared to the full-length receptor (Fig

For an acute injury, users often report effects within a 46 week cycle