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both exhibit broad substrate specificity and overlapping yet distinct regulatory profiles ( While the expression and activity of these CYP isoforms are fundamental to drug metabolism, they exhibit significant interindividual variation, primarily driven by genetic factors

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Consequently, reference intervals for serum GR were established for apparently healthy adults in Eastern China using the ultraviolet enzyme method: 26.651.8 U/l for males and 29.755.3 U/l for females