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Sharief MK, Hentges R (1991) Association between tumor Necrosis factor- and disease progression in patients with multiple sclerosis

In 24 hpi trophozoite-stage parasites, hemoglobin and heme levels were not measurably different, but hemozoin levels were significantly decreased in resistant parasites compared to sensitive parasites (Fig 2B), indicative of decreased turnover of heme into hemozoin in resistant parasites over the preceding 24 h of the parasite lifecycle