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AGEs and neurodegenerative diseases The brain is a highly specialized organ with tightly regulated motor, behavior, neurocognitive, and executive functions

The post hoc analysis of pooled data from the Semaglutide Treatment Effect in People with Obesity (STEP) 1, 2, 3, and 5 trials indicated that semaglutide treatment at 2.4 mg did not increase the risk of depressive symptoms or suicidal ideation compared to placebo, while demonstrating a statistically significant yet clinically negligible decrease in depressive symptoms [75]

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Rasheed H, McKinney C, Stamp LK, et al

Research models suggest its involvement in modulating telomerase-related activity and neuroendocrine regulatory mechanisms under controlled experimental conditions