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Biochemical investigations showed a normal level of cysteinyl glycine in plasma, an abnormal urinary profile with increased excretion of cysteinyl glycine (4972 mmol/mol of creatinine) and leukotrienes with increased leukotriene D4 and complete absence of LTE4

Key symptoms include fatigue, pallor, shortness of breath, neurological manifestations such as paraesthesia (pins and needles), balance problems, memory difficulties, glossitis (sore red tongue), and mood changes

Nevertheless, NACs attractive clinical characteristics (it is inexpensive, is available without a prescription, and is extremely well tolerated), as well as the animal literature indicating that it can attenuate compulsive drug-related behaviors (Kalivas, 2009), have motivated considerable interest in the agent

Current Pharmaceutical Design , 20(7), 11211125

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