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Apart from ER stress, liver-specific overexpression of NACHT, Leucine-rich-repeat and pyrin domain-containing protein 3 (NLRP3) induced marked HSC activation and fibrosis, indicating a possible role of inflammatory cell death in inducing HSC activation (Wree et al., 2014)

Supports lipid metabolism : Aids in the efficient breakdown and utilization of fats

Graham, C

Navab M, Hough G, Buga GM, Su F, Wagner AC, Meriwether D, Chattopadhyay A, Gao F, Grijalva V, Danciger JS, Van Lenten BJ, Org E, Lusis AJ, Pan C, Anantharamaiah GM, Farias-Eisner R, Smyth SS, Reddy ST, Fogelman AM

"Doping control analysis of TB-500, a synthetic version of an active region of thymosin , in equine urine and plasma by liquid chromatography-mass spectrometry"