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It is considered a multipurpose plant: ripe fruits are used in preserves, jellies and beverages (Reference Onilude, Kazeem and Adu14) , while leaves, roots, bark and seeds are used in herbal medicine for malaria, haemorrhages, gastrointestinal disorders, inflammation and metabolic syndrome regulation, among others (Reference Stephen-Onojedje, Ogheneovo Asagba and Kadiri15)

Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice

Moreover, CRF 1 was also detected in all segments of the mouse spinal cord throughout laminae II-V (Korosi et al., 2007)

Tamura et al., FEMS microbiology letters, 99:321, 1992) which affects what is termed the fluidity of the cell membrane as well as the contents of the cell interior (ethanol is a small molecule to which the membrane is partially permeable)

Lobeline a VMAT2 ligand, can modulate dopamine storage and release [37, 38]