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[27] ROSEN, R.C

Brazil nuts come with a big caveat, though

GDNF-expressing macrophages restore motor functions at a severe late-stage, and produce long-term neuroprotective effects at an early-stage of Parkinsons disease in transgenic Parkin Q311X(A) mice

Free mtDNA, ROS, and the MAVS pathway are required for the recruitment of NLRP3 to mitochondrial membranes

Phase 2 placebo-controlled trials are now underway to verify these findings, and the work has prompted the FDA to grant fast-track designation for this indication