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Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora

And citrate actually

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They examine its role in tissue protection, angiogenesis, microvascular stability, and inflammatory signaling

Considered as primary mechanosensors on ECs, signaling through both integrins and cell-cell adhesion molecules can lead to increases in expression of mechanotransductive factors including ERK, Src, and PI3K/Akt, among others (231235)