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5.3 Disease-specific determinants of perinatal glucocorticoid sensitivity Multiple perinatal complications have been associated with fetal/neonatal dysregulation of the HPA axis, cortisol metabolism, and tissue GR expression and function ( Table 3 )

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Notably, the ZFPG + US treatment exhibited the most potent inhibition of metastasis, suggesting that the ZFPG + US mediated sono-metallo-immunotherapy effectively stimulated the bodys immune response, thereby impeding cancer cell metastasis within the body (Fig