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NAC is also an antioxidant itself as a source of sulfhydryl groups in cells and scavenger of free radicals as it interacts with reactive oxygen species such as OH and H 2 O 2 60

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In that study, an aldolase mutant (D34S) which competently binds FBP but prevents enzymatic cleavage into DHAP, preserved lysosomal localisation and activation of mTORC1 in low-glucose conditions