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After completion of the reaction H2A-3 fragment (5.7 mg 1.1 10 3 mmol), dissolved in 100 l of 6 M GnHCl, 200 mM Na 2 HPO 4 , pH~7.2 containing 100 equiv

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10.1126/science.aap7847 Science Summary Keywords malaria, Plasmodium berghei , glutathione S-transferase, drug target, structure-based screening, shape similarity screening, antimalarial drug discovery, predicted pharmacokinetic and toxicity parameters Citation Coln-Lorenzo EE, Coln-Lpez DD, Vega-Rodrguez J, Dupin A, Fidock DA, Baerga-Ortiz A, Ortiz JG, Bosch J and Serrano AE (2020) Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound