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doi: 10.1080/00365521.1970.12096595 108 AnithaMVijay-KumarMSitaramanSVGewirtzATSrinivasanS

Interestingly, preclinical models have shown that curcumin can decrease the expression of Th1 cytokines (IL-12, IFN-gamma, TNF-alpha, IL-1) and increase the expression of Th2 cytokines (IL-4 and IL-10) in colon mucosa, promoting a shift from Th1 to Th2 [510]