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Rating: 4.7461 (27 reviews)

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Description

GPX4 plays an important role in mitophagy, the key step of peripheral reticulocyte maturation and GPX4 deficiency in reticulocytes results in a failure to fully mature

Accumulation of copper has been shown to be associated with tumor cell proliferation (5), angiogenesis (6), and metastasis (7)

Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway