methylglyoxal glutathione reductase Model illustrating the metabolism and detoxification oxidative stress analysis Methylglyoxal-Induced Protection Response and Toxicity:

Structure-activity-relationships of isothiocyanates as mechanism-based inhibitors of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice

doi:10.1111/j.1472-8206.2008.00638.x, PMID: 19207541 Kumar A, Garg R (2008) Kumar P (2008) Nitric oxide modulation mediates the protective effect of trazodone in a mouse model of chronic fatigue syndrome

Owing to the velocity of blood movement through the voxel, MRS does not detect GSH signal from blood, thus, the measured GSH values reflect only GSH in brain parenchyma or CSF

Similarly, aberrant disulfide cross-linking leads to misfolding and subcellular mislocalization of TDP-43 (Barmada et al., 2010

Simulations suggest that glutathione pools are most sensitive to exposure duration at pharmacologically and supra-pharmacologically relevant doxorubicin concentrations