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Liposuction Women with lipedema typically have several medically necessary reasons for undergoing liposuction to remove lipedema fat, including: Loss of mobility Reduced quality of life Joint damage or altered gait Chronic pain Failure to improve signs and symptoms associated with lipedema despite conservative therapy Complete decongestive therapy including manual lymphatic drainage, compression garments, a healthy eating plan, and as much activity as allowed or possible are important before liposuction to improve outcomes