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Major neurodegenerative diseases include Alzheimers disease, Parkinsons disease, multiple sclerosis, and amyotrophic lateral sclerosis [25,26,27,28,29,30,31]

Pain Management: For chronic pain unresponsive to oral medication, IV delivery of analgesics like Ketamine can provide significant relief for conditions like Complex Regional Pain Syndrome (CRPS), fibromyalgia, and neuropathic pain, often reducing the need for opioids

It can cross the BBB as well (Canistro et al., 2010)

Prior to tissue collection, horses were sedated by intravenous administration of detomidine hydrochloride (Dormosedan

It is approved for pleural mesothelioma and non-small cell lung cancer