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On the other hand, the research of Fukuda and co-researchers showed that there was a significant negative correlation between blood ammonia and free carnitine concentrations in epileptic children ( P = 0.003) and this high serum level of ammonia was associated with increased severity of seizures in their series of patients 25

Interestingly, patients in advanced stages of CKD have a reduced ability to excrete ketones in the urine and cope with acid loads

doi: 10.1016/j.pediatrneurol.2006.09.008