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Olsson AG, Schwartz GG, Szarek M, Sasiela WJ, Ezekowitz MD, Ganz P, Oliver MF, Waters D, Zeiher A

The process is dynamic, and involves also the thiolate groups of proteins such as serum albumin and haemoglobin and appears as the main mechanism for the distribution of thiol-binding metals from the absorption site throughout the body and towards the active sites where the toxic action is developed at the molecular level

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Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages