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Given the protective effect of IL-22 on gut barrier integrity and the expansion of IL-22-producing ILC3 in AS, this may suggest anti-inflammatory feedback

Snyder EE, Walts B, Prusse L, Chagnon YC, Weisnagel SJ, Rankinen T, et al

Funding This paper was published as part of a supplement financially supported by Shanghai Municipal Health Commission-Shanghai Sinus Fistula Disease Research Center (2023ZZ02003)

Mechanisms of Ageing and Development Bongiovanni, C., & Baier, L

Major efforts are currently underway to understand the biophysics of CRAC activation, and importantly, to determine if manipulation of CRAC signaling may be of therapeutic benefit