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By observing the ALI model, we could find that MDA expression increased, GSH and GPX4 expression decreased, and mitochondrial morphology changed in order to assess the degree of lung damage caused by ferroptosis at different I/R durations (110, 111)

Currently, some articles have reported that in hepatocytes and tumor cells, the absence of STEAP3 leads to an increase in intracellular iron ion levels, inducing cellular oxidative stress 51

This is due to the fact that GHK is able to inactivate the damaging byproducts released from free radical reactions

doi: 10.1128/MCB.00180-12

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