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Exercise is not strictly required for weight loss on semaglutide, and some people do lose weight without it , but combining semaglutide with resistance training dramatically improves body composition outcomes

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For women in particular, who have fewer well-evidenced options than men, copper peptides represent a gentler exploratory option alongside other approaches

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There is also a small risk of 'serotonin syndrome', a rare but serious condition caused by too much serotonin in the brain