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Description

These findings indicate that multi-targeted drug combinations focused on mitochondrial energy metabolism may be a promising direction for migraine prophylaxis

10.1016/j.cej.2019.123464 45 Hernndez-BuleM

J Neurochem 52: 515520

Conclusion: ALG-055009 is a potent and selective THR- agonist with favorable in vitro safety and ADME properties and repeat-dose toxicity profile in rats and dogs