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In one key example, Hunter et al

SSBs and DSBs were found in rapidly dividing cells such as cancer cells as the collapse of replication fork during DNA replication, leading to cell cycle arrest and apoptosis via activation of p53 (Lee et al., 2016

Instead we chose to analyse a zwf1 strain

In addition, the feasibility of using the prepared system as a dropless approach for glaucoma treatment was assessed ex vivo and on glaucoma-induced rabbit model in vivo