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Evidence also suggests that IL-1 can enhance reactive oxygen species (ROS), in part, through increasing the phosphatidylinositol 3-kinase (PI3-K)/protein kinase B (AKT)/mammalian target of the rapamycin (mTOR) pathwaya pathway implicated in inflammasome activation (125127)

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Furthermore, many cancer cells downregulate acetyl CoA production from pyruvate, requiring cancer cells to also use amino acids as nutrient sources for the TCA cycle

With the ongoing trend of cannabis legalisation globally, there is a demand for research that explores the impact of cannabis and cannabinoids on healthy ageing and diseases of ageing