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We further performed BN-PAGE to detect PKM2 dimers and tetramers in the striatum of Drd2 flox/flox mice and Drd2 hGFAP cKO mice following administration of 5 mg kg 1 quinpirole or 5 mg kg 1 pyridoxine for 7 consecutive days

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The primers cFLIP-F (GTTTTTGGAATTTGATTTAGTTTTGTAG) and cFLIP-B (CCAAAATTAACCAAAAATTACTTCC) were designed to flank the CpG islands of the cFLIP gene and contain at least one restriction site for BstU1

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Furthermore, empirical evidence has shown that the administration of 600 mg of Ashwagandha root on a daily basis over a duration of 12 weeks significantly enhances the quality of sleep, particularly exhibiting heightened efficacy in individuals suffering from insomnia [30]