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Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial

The highest concentrations are found in animal sources, such as meat, dairy, fish and eggs

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Every tirzepatide vial from Empower contains 2mg/mL of niacinamide, a form of vitamin B3 that serves dual purposes

Vial sizes range from a 12 mg starter at $45 to a 180 mg vial at $675, with a flat $39 medical visit fee