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The TgAPParc mouse model, which carries the E693G mutation (APP695) under the control of the murine Thy1.2 promoter, exhibited 3- to 7-fold higher mutant human APP expression compared to endogenous mouse APP

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, Decreasing vitamin D activity (increased phosphoric acid) in decreased production of GSH (Russell-Jones 2024) References Russell-Jones, GJ Altered Metabolism of Iron, Vitamin B, and Vitamin B12 Potentially Interfere with Vitamin D- Activation in Children with Autism

This therapy has strong research support and can produce lasting improvements without ongoing medication or supplementation

Total 1,500 bp sequences upstream from the translational start site of each gene were surveyed to predict cis -acting regulatory elements against the PlantCare database ( Plasmid Construction and Arabidopsis Transformation of RcGPX4 The CDS of RcGPX4 was amplified from the castor bean leaves by real-time (RT)-PCR and inserted into the pCambia1300 expression vector under the control of cauliflower mosaic virus 35S promoter (CaMV 35S) with Kpn I and Xba I linkers using the primers GGGGTACCATGCTTTGTAGTTCTTCAACTAGAT, and GCTCTAGATCACGCAACCCCCAGCAGTTTCTTA