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Description

Activation of peroxisome proliferator-activated receptors and Synergizes with inflammatory signals to enhance adoptive cell therapy

For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)